5 posts tagged “marijuana”

Marijuana/lung cancer: New reporting on potential risks/benefits of cannabis

Posted 3 months ago by

Medical marijuana and cannabidiol (CBD) are getting a lot of media coverage — so what’s the latest, as it relates to lung cancer?

See two recent high-profile articles that weigh the possible risks and benefits of cannabis for cancer and respiratory disease. And add your perspective.

(Psst, checkout past PatientsLikeMe write-ups on medical marijuana and CBD for some background.)

Risk factor or treatment?

Earlier this year, U.S. News & World Report published an article called “Is Marijuana a Risk Factor or a Treatment Option for Lung Cancer?”

Some key points?

  • Marijuana smoke has many of the same toxins as cigarette smoke, so it could harm the lungs. But the doctors and researchers behind a 2017 report say they have not found conclusive evidence showing that smoking cannabis causes lung cancer (some doctors note that it’s difficult to study because many who’ve smoked marijuana have also smoked tobacco, and there are fewer people who are heavy or habitual cannabis users).
  • The 2017 report did show a “slightly higher chance of having adenocarcinoma if you were a habitual [marijuana] smoker than if you were not or a never-user,” but the evidence was still “weak” and not statistically significant, according to doctors involved in the report.
  • Some research (including this 2018 study in the European Journal of Internal Medicine) has shown that cannabis can have a positive effect on symptoms many people undergoing cancer treatment experience, including pain, nausea, sleep problems and decreased appetite. There’s relatively little research in the U.S. on the effects of medical cannabis because it’s still illegal at the federal level and hard to obtain for studies, even in states with medical marijuana laws and CBD laws.
  • The American Cancer Society reminds people that “relying on marijuana alone as treatment while avoiding or delaying conventional medical care for cancer may have serious health consequences.

Another closeup on cannabis

The New York Times also did a deep dive on medical marijuana risks vs. benefits this spring with their article called “It’s Time for a New Discussion of Marijuana’s Risks.”

What are some takeaways related to lung health?

  • Citing a 2005 study, The Times says, “No association was found between smoking marijuana and lung cancer.”
  • Although lung function (in the general population) may actually improve in the short term after smoking cannabis, a long-term look shows that chronic marijuana smoking may harm lung function, research shows.
  • Although marijuana may not have a strong link to cancer, check out the full article for other considerations, such as some increased risks when it comes to certain mental health conditions, short-term memory loss and impaired driving.

Join PatientsLikeMe or sign in to see what members say

Some PatientsLikeMe members with lung cancer have included cannabis and cannabidiol/CBD on their profile as treatments they’ve tried. Logged-in members can see what others have said in the forum about:

Anything to add based on your own experiences? Add a comment below or join the conversation on this topic with others living with lung cancer.

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Marijuana and MS: Get the scoop

Posted 11 months ago by

From legality to availability, recreational use and potential use as treatment, marijuana is a hot topic. In the MS forum, members are talking about marijuana and its potential to relieve symptoms of MS like pain, tremor and spasticity. We wanted to know more, so we asked our Health Data Integrity team to take a look at this topic. So, what is marijuana and how can it impact health and MS? Take a look.

First, a quick refresher: What is Marijuana?

Marijuana is a mixture of dried flowers from the Cannabis sativa or Cannabis indica plants. The marijuana plant contains over 85 cannabinoids that are found in the leaves and buds of the female plant. Cannabinoids are classified as:

  • Phytocannabinoids: found in leaves, flowers, stems, and seeds of the plant.
  • Endogenous: made by the human body.
  • Purified: naturally occurring and purified from plant sources.
  • Synthetic: synthesized in a lab.

Cannabinoids create different effects depending on which receptors they bind to. These chemical compounds are responsible for marijuana’s effects on the body with the most common being delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). Different strains with different combinations and levels of the various cannabinoids along with different methods of consumption give users varied effects.

How does marijuana impact MS?

Despite currently available FDA-approved treatments, many patients with MS still have symptoms. Recent studies suggest treatment with smoked cannabis and oral cannabis extract may improve patient perception of pain and spasticity.

The American Academy of Neurology, conducted a literature review and released a guideline on the use of marijuana in MS patients. This guideline reviews a number of studies where marijuana is used for MS and the findings of this review include:

  • Oral cannabis extract and synthetic THC may be effective for reducing patient-reported symptoms of spasticity and pain, but not bladder symptoms and neuropathic pain.
  • Nabiximols (Sativex®), an oromucosal spray, may be effective in reducing patient-reported spasticity, pain, and urinary frequency, but not urinary incontinence, anxiety symptoms, sleep problems, cognitive symptoms, or fatigue. However, it is important to note that this agent is not currently approved for use in the US.
  • There isn’t enough evidence to fully determine the safety or effectiveness of smoked marijuana in treating any MS symptoms.

If you are interested in reading more studies involving the use of marijuana in MS patients, check out these resources:

  • Long term effects of Sativex® on cognition (click here for more information)
  • Smoked cannabis for spasticity (click here for more information)
  • Dronabinol and pain (click here for more information)

So, what is the takeaway?

While preliminary research shows that marijuana may improve symptoms in patients with MS, more extensive clinical trials are in progress to evaluate the safety, efficacy, and dose of cannabis for patients with MS.

One of these studies is currently recruiting participants to investigate the effects of medical marijuana usage on physical functions on MS patients. To find out if you qualify and the location of the study, click here for more information.

Long-term safety of marijuana use for symptom management for patients with MS is not fully known. So, patients should be aware of the pros and cons of this treatment option and discuss the use of medical marijuana with their healthcare provider. While there are benefits that marijuana may provide for patients, there are many side effects that may limit the use of this therapy.

Most common side effects include:

  • Dizziness
  • Drowsiness
  • Difficulty concentrating
  • Memory disturbance
  • Changes in mood

Source: https://www.drugabuse.gov/publications/drugfacts/marijuana

Want to know more?

Sources:

https://www.cancer.gov/publications/dictionaries/cancer-terms/http://www.neurology.org/content/82/12/1083.full.pdf+htmlhttps://www.leafly.com/news/health/how-marijuana-affects-the-brainhttps://www.nationalmssociety.org/Treating-MS/Complementary-Alternative-Medicines/Marijuanahttps://www.drugabuse.gov/drugs-abuse/marijuana/nih-research-marijuana-cannabinoids

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