Available without a prescription in France, Euphytose is an herbal treatment for anxiety and depression that contains six plant extracts:  Hawthorn, Passionflower, Valerian, Ballota foetida, Cola nitida and Guarana (Paullinia cupana).  The latter is available in France as an over-the-counter anxiolytic (anti-anxiety) agent.

Producing both sedative and stimulant effects, Euphytose combines traditional herbal remedies for anxiety with components that are thought to act on central benzodiazepine receptors.  It had been studied in one short, double-blind, placebo-controlled trial involving 181 adults, with a statistically significant effect found for both reduction in symptoms and clinical response to Euphytose over placebo at the end of the trial.  In terms of safety, it was well-tolerated in the study with no difference in the number of adverse effects compared with placebo – and no serious adverse effects.

At PatientsLikeMe, where more than 125,000 patients are sharing their experiences with all types of treatments, two patients report trying Euphytose.   The reported purposes were “Anxious mood,” “Panic disorder” and “Insomnia.”  Effectiveness was rated as either “Moderate” or “Slight,” while side effects included “Drowsiness” and “Problems concentrating.”  Here’s what one patient with panic disorder wrote on his Euphytose treatment evaluation:  Makes you a little drowsy, but helps in limiting the effects of expected stressful situations.”

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Metoprolol Succ ER (the common abbreviation for Metoprolol Succinate ER and a generic form of Toprol XL) is an extended release formulation of the drug metoprolol, which is used for the treatment of angina or hypertension and to reduce mortality/hospitalization in patients with heart failure who are already receiving cardiac and diuretic medications.

At PatientsLikeMe, where more than 120,000 patients are sharing their experiences with conditions, symptoms, treatments and more, 185 patients report using Metoprolol Succ ER.  What can we learn from these patients’ experiences?  Quite a bit, actually, thanks to PatientsLikeMe’s unique data-sharing platform.  For example, the most commonly reported duration amongst current users is two years or more, while the most commonly reported dosage at PatientsLikeMe is 50mg daily.

Wondering about Metoprolol Succ ER side effects?  Some of the commonly reported side effects include loss of energy, fatigue, excessive daytime drowsiness and weight gain.  Check out the 29 treatment evaluations of Metoprolol Succ ER submitted by our patients to gain even more insight.  For example, the following are several tips submitted by Metroprolol Succ ER users on their evaluations:

• “Remember to get up slowly.  [This drug] has been making me very light headed and dizzy.  Also be sure to hydrate frequently.”

• “Try to take it everyday at the same time – I am really bad at this, so I’ve started taking at night.”

• “When I miss a dose or two, I get an instant, awful, pounding headache on the top of my head, as my blood pressure goes through the roof, and my ears turn beet red and I can literally feel the heat coming off of them.”

• “Be prepared to feel cold physically when taking this medication. Dress warmly even when in air conditioning.”

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ADCO Mirteron is an international brand of mirtazapine, a tetracyclic antidepressant that is used to treat depression and, in come cases, insomnia.  At PatientsLikeMe, where more than 115,000 patients are sharing their experiences with prescription drugs, supplements and more, we have just one patient who reports taking ADCO Mirteron while more than 300 patients report taking another branded or generic formulation of mirtazapine. (Other brand names include Remeron, Avanza, Zispin, Axit, Mirzaten and Rexer.)

What can we learn from these patients’ experiences?  Quite a bit, actually, thanks to PatientsLikeMe’s unique data-sharing platform.  For example, the most commonly reported dosage of mirtazapine is 15mg daily, the most commonly reported cost is “under $25,” and the most commonly reported side effects include weight gain, increased appetite and drowsiness.  153 of our patients have discontinued mirtazapine, with side effects, lack of efficacy and doctor’s advice among the top reasons cited.

Here are some highlights from the 130 treatment evaluations our patients have submitted for mirtazapine (the generic form of ADCO Mirteron):

• “After trying almost every other depression med and mood stabilizer out there, this is the one that’s worked well for me. Wish I had found it sooner.” – Patient with major depressive disorder

• “I take this medicine to help me sleep at night, but it also helps a bit with my depression and anxiety.” – Patient with fibromyalgia

• “Works well, but leaves me a little sleepy or slow throughout the day. Need to make sure you get 8-9 hours sleep or the sleepy feeling stays with you all day.” – Patient with post-traumatic stress disorder (PTSD)

• “Very hungry when taking this med. I take 30mg in the morning and by 2pm I have had my total daily allowance of calories!” – Patient with general anxiety disorder (GAD)

• “When I was depressed, it was very effective and my body adjusted to the sedation effects. As my depression lifted, I experienced more and more difficulty in waking up.” - Patient with bipolar disorder

• “I can see why other people can have problems with the constant drowsiness and increased appetite/weight gain, but for an anxious under-eating insomniac like me, it was ideal.” – Patient with major depressive disorder

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Have you taken ADCO Mirteron – or another brand of mirtazapine?  Join PatientsLikeMe and add your experiences to our growing body of knowledge.  Then, stay for the support.  With nearly 30,000 members who report a mental health condition, we have a tremendous amount of discussion and activity in our Mental Health and Behavior Forum.  Chime in today.