223 posts in the category “Multiple Sclerosis”

Probiotics for MS? The latest research

Posted May 23rd, 2018 by

Wondering if a probiotic could help treat your MS? With 10 forum threads on the topic, you’re not the only one. From conflicting information online to recommendations from friends and new research making headlines, separating fact from fiction can be tricky. Here’s a recap of the latest research on probiotics and MS from our in-house team of health professionals.

Let’s start with the basics: What are probiotics?

Probiotics are live microorganisms (usually bacteria or yeast) that may be able to help prevent and treat some illnesses and encourage a healthy digestive tract and immune system. They’re often referred to as “gut-friendly” bacteria.

  • Where can you get them? Probiotics are often in supplements or foods (like yogurt, kefir, kimchi, tempeh, etc.) that are prepared by bacterial fermentation.
  • A couple probiotic bacteria that have been shown to have health benefits include: Lactobacillus and Bifidobacterium. Within those groups are many different species and strains. Many probiotic supplements (broad-spectrum or multi-probiotics) combine different species together in the same supplement.
  • Gut flora (microbiota) consists of hundreds of different types of microorganisms. Probiotics may help improve the way your gut flora performs.
Why is gut health important for MS?
  • Your gut does more than digest food — it plays an essential role in the immune system.
  • There are both anti-inflammatory microbes and microbes that cause inflammation by adding stress to the immune system. When your gut bacteria is out of balance, it can have a negative impact on your health.
  • Some research shows, an MS gut may have more pro-inflammatory bacteria like Methanobrevibacter and Akkermansiaas and less anti-inflammatory bacteria like Butyricimonas.
  • Newer research shows there may be a link between gut flora and the progression of MS.
The latest research on probiotics for MS
  • While there have been studies in mice models and bacteria, there are only two clinical trials that have studied the effects of probiotics in patients with MS.
  • pilot study tested 22 patient fecal samples before and after administering VSL3 (a probiotic mixture with 8 strains of lactic acid–producing bacteria including: L. plantarum, L. delbrueckii subsp. Bulgaricus and L. acidophilus) for markers of inflammation which has been associated with the progression of MS.
    • Results: There was an increased anti-inflammatory effect in the cells after administration of probiotic.
  • randomized controlled trial treated 60 patients with a probiotic containing Lactobacillus acidophilus, Lactobacillus casei, Bifidobacterium bifidum and Lactobacillus fermentum.
    • Results: The study demonstrated that the use of probiotic capsule for 12 weeks among patients with MS had favorable effects on EDSS (Expanded Disability Status Scale), mental health, and inflammatory factors.
    • Based on the results, the difference in EDSS levels between treatment and placebo was statistically significant, however, was not clinically significant (meaning, we need more evidence).
The bottom line:

Should you start taking a probiotic? The jury’s still out. Based on the two trials and the other non-patient studies, there seems to be a link between gut flora and the progression of MS. However, at this time there isn’t enough data or clinical benefit to support the use of probiotics for MS.

Considering taking a probiotic to treat your MS? Be sure to talk to your doctor.

Have you tried taking a probiotic to treat your MS? Join PatientsLikeMe and share your experience with the community.

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Health news: What’s making headlines this month

Posted May 8th, 2018 by

Let’s stay on top of the latest health news — in case you missed it, check out this round up of some of the stories making headlines in May.

ALS
  • May is ALS awareness month: Later this month, advocates from across the U.S. will head to Capitol Hill to meet with their legislators. Check out how you can get involved and join the fight against ALS.
  • Congress passes $3 billion increase in NIH funding: $140 million of the increase will go to the BRAIN Initiative research projects that contribute to the knowledge and understanding of ALS. More info.
Lupus
  • May is Lupus Awareness Month: Nearly two-thirds of people know little or nothing about lupus beyond the name, according to the Lupus Foundation of America, which is promoting the “Go Purple” campaign. Get ideas for boosting awareness.

  • A link between the “mono” virus and lupus? A new study published in Nature Genetics shows that the Epstein-Barr virus (EBV) — known for causing mononucleosis — may increase the risk of lupus and six other autoimmune diseases by changing how some genes are expressed. Check it out.
Parkinson’s Disease
  • “Suspect” Parkinson’s drug faces scrutiny: Following reports of hundreds of deaths and adverse events, the FDA is re-examining the safety of Nuplazid (pimavanserin), which was approved in 2016 for treating hallucinations and delusions associated with PD. Read more.
Lung cancer
  • Emerging treatments for small-cell lung cancer (SCLC): Immunotherapy and other emerging drugs called PARP inhibitors and Rova-T(Rovalpituzumab tesirine) are among a group of new therapies showing “early promise” in clinical trials for the treatment of patients with SCLC. Hear from one patient.
MS
  • Life after a stem cell transplant: The BBC’s Caroline Wyatt had a stem cell transplant in Mexico to reboot her immune system. A year later, she shares how she’s doing. Read Caroline’s story.
  • New drug for secondary progressive MS: Phase 3 clinical trial results show that a new drug could slow down the progression of symptoms for people living with secondary progressive MS. Get the scoop.
Mental health
  • Ever heard of forest bathing? Research from the Nippon Medical School in Tokyo found that just standing in the woods could reduce depression scores and improve immune function. They also found some surprising benefits of dirt… Get the full story.
  • Looking closer at medical marijuana strains and doses: A new study draws from user-reported data on marijuana smoking habits to understand the effect of weed on depression and anxiety. From different strains to number of “puffs,” see what was uncovered.
  • Combining treatments for better results: Researchers at the University of Texas found they could boost the positive effects of cognitive processing therapy (CPT) by adding transcranial magnetic stimulation. More info.

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