Comments on: New Parkinson’s Genetics Engine to Enhance Research Through Shared Data http://blog.patientslikeme.com/2009/08/20/new-parkinson%e2%80%99s-genetics-engine-to-enhance-research-through-shared-data/ PatientsLikeMe - Patients helping patients live better every day Wed, 16 May 2012 21:10:48 +0000 http://wordpress.org/?v=2.7 hourly 1 By: cbrownstein http://blog.patientslikeme.com/2009/08/20/new-parkinson%e2%80%99s-genetics-engine-to-enhance-research-through-shared-data/comment-page-1/#comment-43209 cbrownstein Wed, 29 Sep 2010 15:08:52 +0000 http://blog.patientslikeme.com/?p=1096#comment-43209 Dear Pat, Thanks for writing. Unfortunately we are not able to provide medical advice, but your medical provider should be able to recommend a plan for you and your siblings to get tested for Parkinson's and dementia. I did a search on Pubmed, and found an article that concluded that Parkinson's disease appeared more frequently in people with Epilepsy (Gaitatzis et al., 2004); however, a co-morbidity study found that Epilepsy is *less* likely in individuals with Parkinsonism, especially Parkinson's disease (Bodenmann et al., 2001). Interestingly, another paper noted a reduction in seizure frequency with the development of parkinsonian symptoms (Vercueil, 2000). I have heard of "Parkinson's Plus" syndromes being associated with seizures in patients (Nygaard et al., 1989), though it is not clear whether the seizures are epileptic, or just associated with the progression of the disease. I guess it is safe to say the jury is still out on this one. Hope this helps a bit. If you have more questions, please feel free to email me! Sincerely, Catherine Catherine Brownstein MPH, PhD Dear Pat,
Thanks for writing. Unfortunately we are not able to provide medical advice, but your medical provider should be able to recommend a plan for you and your siblings to get tested for Parkinson’s and dementia.

I did a search on Pubmed, and found an article that concluded that Parkinson’s disease appeared more frequently in people with Epilepsy (Gaitatzis et al., 2004); however, a co-morbidity study found that Epilepsy is *less* likely in individuals with Parkinsonism, especially Parkinson’s disease (Bodenmann et al., 2001). Interestingly, another paper noted a reduction in seizure frequency with the development of parkinsonian symptoms (Vercueil, 2000).

I have heard of “Parkinson’s Plus” syndromes being associated with seizures in patients (Nygaard et al., 1989), though it is not clear whether the seizures are epileptic, or just associated with the progression of the disease.

I guess it is safe to say the jury is still out on this one.

Hope this helps a bit. If you have more questions, please feel free to email me!
Sincerely,
Catherine
Catherine Brownstein MPH, PhD

]]> By: Patricia http://blog.patientslikeme.com/2009/08/20/new-parkinson%e2%80%99s-genetics-engine-to-enhance-research-through-shared-data/comment-page-1/#comment-42073 Patricia Mon, 20 Sep 2010 04:54:45 +0000 http://blog.patientslikeme.com/?p=1096#comment-42073 My paternal grandfather had late on set parkinson's my grandfather died at 69. I am not sure as to the type or the extend of the disease however it was back in the late 60's when he was diagonses and was told there was not help for him as he was in the advanced stages at that time. My father was showing signs of dementia years before his death 69 years old. How do my siblings and myself get tested we are in our late 50's and early 60's? What test do we need to request and from what type of doctor? I have not heard of any research in to linking Parkinson's and Epilepsy as my son has epilepsy that is not controlled since the age of 5 years old. I search continuelly for answers and guideance. Cordially Pat My paternal grandfather had late on set parkinson’s my grandfather died at 69. I am not sure as to the type or the extend of the disease however it was back in the late 60’s when he was diagonses and was told there was not help for him as he was in the advanced stages at that time. My father was showing signs of dementia years before his death 69 years old. How do my siblings and myself get tested we are in our late 50’s and early 60’s? What test do we need to request and from what type of doctor? I have not heard of any research in to linking Parkinson’s and Epilepsy as my son has epilepsy that is not controlled since the age of 5 years old. I search continuelly for answers and guideance.
Cordially
Pat

]]> By: cbrownstein http://blog.patientslikeme.com/2009/08/20/new-parkinson%e2%80%99s-genetics-engine-to-enhance-research-through-shared-data/comment-page-1/#comment-30774 cbrownstein Mon, 08 Feb 2010 19:28:09 +0000 http://blog.patientslikeme.com/?p=1096#comment-30774 Dear Ms. Cherubino, Thank you for your comment. You can find out your mutation through your medical provider, who may refer you to a Genetic Counselor for the test and interpretation of the results. Unfortunately, we are unable to provide medical advice, but he or she should be able to answer your questions about Parkinson's Disease and adhesive capsulitis. Best wishes, Catherine Brownstein MPH, PhD Dear Ms. Cherubino,

Thank you for your comment. You can find out your mutation through your medical provider, who may refer you to a Genetic Counselor for the test and interpretation of the results. Unfortunately, we are unable to provide medical advice, but he or she should be able to answer your questions about Parkinson’s Disease and adhesive capsulitis.
Best wishes,
Catherine Brownstein MPH, PhD

]]> By: Sadie Cherubino http://blog.patientslikeme.com/2009/08/20/new-parkinson%e2%80%99s-genetics-engine-to-enhance-research-through-shared-data/comment-page-1/#comment-30233 Sadie Cherubino Wed, 03 Feb 2010 21:57:33 +0000 http://blog.patientslikeme.com/?p=1096#comment-30233 How do we find out about our mutation nnumbers and what does it mean? Also what is drug induced Parkinsons and vascular parkinsons? My daughter just informed me that she feels she is at high risk for Parkinsons because of he r having adhesive capsulitis, what is this about. Please respond to this. Thank you Sadie Cherubino How do we find out about our mutation nnumbers and what does it mean? Also what is drug induced Parkinsons and vascular parkinsons? My daughter just informed me that she feels she is at high risk for Parkinsons because of he r having adhesive capsulitis, what is this about. Please respond to this. Thank you Sadie Cherubino

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